External quality assurance of drug resistance PDF Print E-mail

The main purpose of External Quality Assurance (EQA) of drug resistance is to determine the uniformity and reproducibility of conventional procedures of drug susceptibility testing of M. tuberculosis for first-line drugs. The proficiency testing programme between the CTRL and Supra National Reference Laboratory (SNRL) at the Institute of Tropical Medicine- Antwerp, Belgium is an ongoing activity which is providing quality assurance for anti-tuberculosis drug resistance surveillance. A panel set of 20 strains of different resistant patterns were received at CTRL for rechecking in December 2010. The tests were done for the 4 first-line anti-TB drugs (Isoniazid, Rifampicin, Ethambutol and Streptomycin). The feedback for these susceptibility testing results is was not good apparently due to contamination or mishandling and possibly inexperience and lack of technical knowhow on the part of tester. Hence could not give the actual representative of the laboratory, this could be due to mishandling of the samples or technique know how.

Last Updated on Monday, 04 March 2013 13:42